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Little clicked for the Bills' quarterback in a frustrating game Thursday night against the Houston Texans.

And still he nearly managed to driving the Bills to a win before an interception in the final minute ended their hopes in a close loss.

Allen endured consecutive sacks on the Bills’ final possession, leading to a long fourth down, but Buffalo (7-4) picked up significant yardage on a quick throw from Josh Allen to a receiver, who tossed a backward pass to Khalil Shakir.

Following a pre-snap infraction created a fourth down situation for Buffalo, a Texans defender picked off the quarterback's throw at the 9-yard line with 24 seconds remaining.

We possessed a chance to come out on top there at the end,” Allen stated. “Our team performed a solid job of hanging tough and our defense bailed us out a few instances. We’ve got figure it out, and unfortunately we failed.”

It was tough for the signal-caller to get anything going on a evening he was brought down a career-high eight times and hit four other times. The QB threw for 253 passing yards with a pair of picks and zero scores after producing six touchdowns in a win over Tampa Bay last week.

Whenever they pressure our QB a dozen times, I don’t like that,” Bills coach Sean McDermott said. “I disapprove of that stat at all. It is not a healthy way to compete and it’s not a good way to keep our field general in good shape for the rest of the season. We need to play better.”

Josh Allen was sluggish to rise after a tackle in the first half. He said he was fine and that his shoulder “lost some feeling” after he landed on it in an awkward manner. He was asked about being contacted so many times during the game.

“It’s not fun,” he said. “I ran into a couple personally. I need to be better at disposing of the football. On multiple occasions, I found myself losing ground.”

The Bills' QB surrendered 70 yards on the eight sacks. Anderson had 2.5 tackles for loss to lead the Texans. His second one occurred when he nearly took Allen down near the scrimmage line, but he escaped and Anderson rose and pursued him downfield to drop him for an 18-yard deficit to result in a punt early in the third.

The Bills played for a second straight game without receiver Keon Coleman after he was once more a healthy scratch after he was tardy to a team meeting before their last game. He was previously held out for the first series of a loss to New England in Week 5 after additionally being delayed for a meeting.

No change. We’re just approaching it one day at a time,” McDermott said. “I thought he had a improved week, but we’re handling it one day at a time. It was not that it was ignored, but we went with the guys that give us the best chance.”

Khalil Shakir led the Buffalo with eight catches for 110 receiving yards and James Cook had 116 yards and a touchdown.

The quarterback was frustrated that the team couldn’t make plays down the stretch.

In the end, we’ve got perform, and we failed to do a good job of that this evening,” he said. “Whatever situation and whatever condition, we need to find a way, and we didn’t.”